Medical intern Calvin Stowe has been making a nuisance of himself, getting shunted from one department to the next by his arrogance and disrespect for the women of the Edelman-Carter Institute. When a particularly crude remark about his female superior's ass proves the last straw, she recommends that he be transferred to work with Dr. Sandra Elby, the famous researcher. Convinced he's been promoted, he smugly arrives on the third floor to begin work, only to learn that he's being recommended not as a lab assistant, but as a test subject.

He's unclear what exactly these trials entail, but he's told it's his last chance to walk out the doors with a good recommendation, so he decides to go along with it. By the time he realizes the changes that are happening to him, it's too late to back out. Soon, the new hormones and pleasure treatments designed to make him more feminine and docile have him forgetting he ever wanted to leave in the first place, and what was once the office jerk will soon be the lab bimbo: horny, submissive, and eager to please any man who walks through the door.

Reader Advisory: This story is for mature audiences only and features intensely erotic situations, femdom humiliation, feminization gender swap, bimbofication and the use of potent aphrodisiacs, multiple partners and rough group sex, sexual manipulation, submissiveness and dominance. All characters are 18 or older.